Meridia (Sibutramine 15mg)

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Meridia Medical Drug Dosage form: 15mg tablet, 30mg capsule
Meridia (Sibutramine 15mg)

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About

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Meridia is a Medical drug in the class of serotonin norepinephrine reuptake inhibitor which is used in the treatment of obesity. The active ingredient present in Meridia Medical drug is Sibutramine 15mg. This Medical drug has ability to reduce weight by decreasing appetite, increasing energy levels, burning lipids and inhibiting their absorption from alimentary tract.

Sibutramine Medical Drug causes reduction of intake of carbs through inhibition of serotonin reuptake that results in an increased level of serotonin in the brain because it prevents dispersal into blood stream. It also inhibits the release of chemical messengers for hunger known as Neuropeptide Y (NPY) completely preventing food craving. Sibutramine Medical Drug works by passing into the brain and interfering with your normal hunger and satiety cues.

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This Medical drug also causes burning of lipids and inhibiting their absorption from alimentary tract which results in weight loss. This Medical Drug reduces body weight both through its action on appetite suppression as well as calorie reduction.

Increase in energy levels is due to metabolic changes such as increased thermogenesis, fatty acid oxidation, glycogenolysis etc. Thermogenesis is the process of heat production in living organisms. Activation of Dopaminergic receptors increases heart rate causing increased thermogenesis increasing energy levels and stimulating digestive system resulting in lipolysis (breakdown & release of fat)

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Meridia Medical Drug should administer orally once daily before breakfast or one hour after breakfast. It may be taken with or without food. The tablet should be swallowed whole not chewed or broken, if chewed or broken it won’t work effectively Medical Drug.

Meridia Medical Drug is contraindicated in case of patients having Gastrointestinal obstruction, Hypersensitivity to Meridia Medical Drug, Pheochromocytoma (Pigmented tumor on adrenal gland), Concomitant use of MAO inhibitors within last 14 days and narrow-angle glaucoma.

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This Medical drug can cause dizziness headache sweating nausea dry mouth insomnia palpitations fatigue urinary tract infections etc symptoms which will go away by themselves are not a reason to stop taking Sibutramine 15mg Medical Drug.

It is important to note that this Medical Drug is not meant for weight loss in children under 18 years of age. This Medical drug should be used only when the net difference between an individual’s total caloric intake and his caloric expenditure warrants treatment with Sibutramine Medical Drug in order to lose weight Medical Drug.

Meridia Medical Drugs dosage indication include Obesity, Weight control along with dietary changes for chronic weight management Medical Drug.

Side effects of Meridia Medical Drug are dizziness headache sweating nausea dry mouth insomnia palpitations fatigue urinary tract infections etc. Itching Difficulty in breathing Infection Nervousness Joint Pain Gas Pain in stomach

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Sibutramine, formerly sold under the brand name Meridia among others, is an appetite suppressant which has been discontinued in many countries. Until 2010, it was widely marketed and prescribed as an adjunct in the treatment of obesity along with diet and exercise. It has been associated with increased cardiovascular events and strokes and has been withdrawn from the market in several countries and regions including Australia,[1] Canada,[2] China,[3] the European Union,[4] Hong Kong,[5] India,[6] MexicoNew Zealand,[7] the Philippines,[8] Thailand,[9] the United Kingdom,[10] and the United States.[11] However, the drug remains available in some countries.[12]

Origin of Sibutramine 15mg Pills

Sibutramine was originally developed in 1988 by Boots in Nottingham, UK,[13] and marketed by Knoll Pharmaceuticals after BASF/Knoll AG purchased the Boots Research Division in 1995, and was most recently manufactured and marketed by Abbott Laboratories before its withdrawal from most markets. It has been sold under a variety of brand names including Reductil, Meridia, Siredia, and Sibutrex. It is classified as a Schedule IV controlled substance in the United States.

Medical uses Of Meridia (Sibutramine 15mg)

Sibutramine has been used to produce appetite suppression for the purpose of attaining weight loss in the treatment of patients with obesity.

Contraindications

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Sibutramine is contraindicated in patients with:

Side effects of Meridia (Sibutramine 15mg)

A higher number of cardiovascular events has been observed in people taking sibutramine versus control (11.4% vs. 10.0%).[15] In 2010 the FDA noted the concerns that sibutramine increases the risk of heart attacks and strokes in patients with a history of cardiovascular disease.

Frequently encountered side effects are dry mouth, paradoxically increased appetite, nauseastrange taste in the mouth, upset stomach, constipation, trouble sleeping, dizziness, drowsiness, menstrual cramps/pain, headache, flushing, or joint/muscle pain.

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In a 2016 Cochrane review sibutramine was found to substantially increase blood pressure and heart rate in some patients, in the updated review in 2021 sibutramine was not included since the drug had been withdrawn from the market.[16] When used, regular blood pressure monitoring needed to be performed.

The following side effects are infrequent but serious and require immediate medical attention: cardiac arrhythmias, paresthesia, mental/mood changes (e.g., excitement, restlessness, confusion, depression, rare thoughts of suicide).

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Symptoms that require urgent medical attention are seizures, problems urinating, abnormal bruising or bleeding, melenahematemesisjaundicefever and rigorschest painhemiplegia, abnormal vision, dyspnea and edema.

Currently, no case of pulmonary hypertension has been noted. (Fenfluramine, of the 1990s “Fen-Phen” combo, forced excess release of neurotransmitters—a different action. Phentermine was uninvolved in the rare—but clinically significant—heart issues of fenfluramine.)

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